The interchange was named the winner of the Medium Category at the North West Institute Structural Awards during a ceremony in Manchester.
The £13.5m development provides a strategic link to Chester and the wider area while also acting as a transport node to the proposed £300m Northgate development.
The interchange expects to serve 1,020 bus movements per day, including national coach journeys, with an anticipated reduction in congestion and an improved user interface for rail users, pedestrians and cyclists.
The striking design incorporates glulam timber beams to create a curved roof form, providing visual interest from within the passenger waiting environment.
The roof itself is covered with an extensive sedum system which adds an element of green space to complement the nearby Cathedral.
Project director for the project Phillip Pollington said: “Chester Interchange deserves to win an award not only for its striking design but also for its vital role in improving the public transport infrastructure of Chester. It’s really exciting for Jefferson Sheard to be part of this development, which is just the beginning of an exciting new chapter for Chester.”